C. elegans is a useful animal model for human diseases because around 40% of its genes are orthologous to those of humans. It has a short life cycle of about 3 days at 20˚C and is amenable to culture with E. coli. Further, C. elegans has only about 1,000 somatic cells, the cell lineages of which have been comprehensively described. Thanks to serial electron microscopic images, detailed descriptions of its morphology have also been produced, and it was the first multicellular organism to have its whole genome sequenced. Thus, C. elegans is suitable for genetic analyses, and its mutants are useful for exploring gene function.
・Deletion mutant lines: about 13,100 lines
・High function balancers: 69 lines
・Cre transgenic lines: 43 lines
Subjects in the NBRP programs “Genome information upgrading program” and “Fundamental technology upgrading program” related to “C. elegans”
【 Fundamental technology upgrading program 】