|Focus||Genome sequencing of diverse Drosophila species (II)|
|Principal Investigator||Shu Kondo Genetic Resource Center, National Institute of Genetics|
Drosophilidae is an extremely diverse family of insets, with an estimated 10,000 species distributed all over the world. The most famous member of this family is Drosophila melanogaster, one of the most important model organisms in biomedical research. D. melanogaster was originally endemic to tropical sub-Saharan Africa, which offers a very comfortable environment for animals. In contrast, there are species of Drosophila that have adapted to extreme environments: Some species inhabit subarctic zones while others inhabit dessert areas. There are also species that evolved to specialize in toxic food such as poisonous mushrooms. Not a few of these interesting species can be cultured in the laboratory just like D. melanogaster, offering a unique opportunity to study the molecular genetics of a new biological phenomenon. In the previous year, we determined the genome sequences of 10 Drosophila species. This year we will perform RNA-seq analysis of these species to comprehensively obtain the sequences of expressed mRNAs. Using the obtained data, we will annotate the genome sequence of each of the 10 species.